tools
PathExplore
AI software that analyzes H&E whole-slide images to quantify tumor microenvironment features at single-cell resolution.
PathExplore analyzes hematoxylin and eosin whole-slide images, segmenting tissue regions and classifying cells to produce standardized human-interpretable features about the tumor microenvironment. It measures cell counts, tissue areas, densities, spatial distributions, and nuclear morphology.
It is used by biopharma teams, academic medical centers, and translational researchers for biomarker discovery, tumor biology studies, cohort analysis, and treatment-response research. PathExplore is for research use only, not diagnostic procedures. PathAI does not publish standard pricing; academic access to TCGA-derived HIF data is free, while non-academic access is licensed.
Features
- Analyzes H&E whole-slide images at pixel and single-cell resolution
- Segments tissue regions and classifies cancer cells, fibroblasts, and lymphocytes
- Generates over 600 human-interpretable histopathology features
- Measures cell counts, tissue areas, densities, and spatial relationships
- Captures nuclear size, shape, solidity, and stain intensity
- Provides tumor segmentation and immune-cell prediction overlays
- Supports bulk analysis of large H&E image cohorts through AISight
- Research use only; not for diagnostic procedures
Use cases
- Discover histological biomarkers linked to molecular measurements
- Quantify tumor-infiltrating lymphocytes and immune-cell distributions
- Compare tumor microenvironment features across treatment cohorts
- Study associations between tissue morphology and patient outcomes
- Analyze TCGA pathology data alongside clinical and molecular data
- Support translational research and clinical-development studies